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Forschung im BioMEMS lab

Themen

Das wissenschaftliche Interesse der Arbeitsgruppe fokussiert sich auf neuronale Biosensoren und die Entwicklung von Algorithmen zur Auswertung elektrophysiologischer Daten.

Geförderte Projekte

  • Laufend

    • Untersuchung der Wirkung von psychedelischen Substanzen auf neuronale dreidimensionale Zellkulturen, 2024 - 2027, DFG.
    • ESTRANGE Gehirn-Assembloide als Modell zur Untersuchung von strahleninduzierten neuropsyiologischen Erkrankungen, 2023 - 2026, BMBF in Kooperation mit GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt.
    • Biologisch abbaubare und umweltfreundliche Sensoren basierend auf Polymilchsäure Ferroelektreten mit einstellbarer Lebensdauer 2023 - 2026, DFG, in Kooperation mit der TU Darmstadt.
    • BioBAT Biologisch abbaubare Batterien, 2024 - 2026,  NETZ Transferzentrum der THAB. 
    • Konfokales Laser-Scanning-Mikroskop mit Lichtblattmodul für die Analyse neuronaler dreidimensionaler Zellkulturen und Organoide, 2023 - 2025, DFG.
    • iNeuTox Humane induziert-pluripotente stammzellbasierte, neuronale 3D-Zellkulturmodelle zum funktionellen In-Vitro-Screening, 2019 - 2024, BMBF.
    • KIsS Plattform zur KI-gestützten Sensordatenanalyse, 2022 - 2024, BMBF.
  • Abgeschlossen

    • Brain Radiation Assay Etablierung eines in vitro Systems zur Analyse und Prädiktion von Schäden im zentralen Nervensystem nach Exposition mit ionisierender Strahlung in Kombination mit anderen Neurotoxika, 2019-2023, BMBF, in Kooperation mit GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt.
    • KANIS Kooperative Autonome Intralogistik-Systeme, 2020 - 2023, Bayerisches Wirtschaftsministerium, in Kooperation mit Kollegen der THAB und der Linde GmbH.

Publikationen

  • 2024

    • Dennis Flachs, Sergey Zhukov, Isabella Zech, Timo Schreck, Stefan Belle, Heinz von Seggern, Mario Kupnik, Alexander Anton Altmann, Christiane Thielemann, Enzymatic Self-Degradable PLA-Based Electrets. Journal of Polymers and the Environment, 2024, open access.
    • Caroline Alves, Manuel Ciba, Thaise G L de O. Toutain, Joel Augusto Moura Porto, Eduardo Pondé de Sena, Christiane Thielemann, Francisco A Rodrigues, On the advances in machine learning and complex network measures to an EEG dataset from DMT experiments, Journal of Physics: Complexity, 2024, open acess.
    • Trent Davis, ..., Christiane Thielemann, ... Monica Monici, 2024. How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?, nature npj Microgravity, open access.
  • 2023

    • Caroline Alves, Thaise Toutain, Patricia Aguiar, Aruane M. Pineda, Kirstin Roster, Christiane Thielemann, Joel Porto, Francisco A. Rodrigues, Diagnosis of autism spectrum disorder based on functional brain networks and machine learning. Scientific Reports. 2023 (13/8072),  open access.
    • Christiane Thielemann, Nenad Krstić, Jens Jüttner, Lars Giegerich, Margot Mayer, Monika Knuth, Achim Müller, 3D printed biosensor for continuous glucose measurement in cell cultures. Annals of 3D Printed Medicine. 2023, open access.  
    • Caroline Alves, Thaise Toutain, Joel Porto, Patricia Aguiar, Eduardo de Sena, Francisco A. Rodrigues, Aruane M. Pineda, Christiane Thielemann, Analysis of functional connectivity using machine learning and deep learning in different data modalities from individuals with schizophrenia. Journal of Neural Engineering. 2023 (20/5), open access.
    • Monica Monici, Christiane Thielemann, How do gravity alterations affect animal and human systems at a cellular/tissue level?. nature npj Microgravity. 2023 (9/84), open access
  • 2022

    • Dennis Flachs, Florian Emmerich, Christiane Thielemann, Fabrication process for FEP piezoelectrets based on photolithographically structured thermoforming templates,  Microsystem Technologies, 29, 2023, open access.
    • Caroline Alves, Rubens G. Cury, Kirstin Roster, Aruane M. Pineda, Francisco A. Rodrigues, Christiane Thielemann, Manuel Ciba, Application of machine learning and complex network measures to an EEG dataset from ayahuasca experiments, PLOS ONE. 2022 (12), open access.
    • Dennis Flachs, Johannes Etzel, Margot Mayer, Frederic Harbecke, Stefan Belle, Tim Rickmeyer, Christiane Thielemann, Characterization of electrically conductive, printable ink based on alginate hydrogel and graphene nanoplatelets. Biomedical Engineering Advances. 2022 (4),  open access
    • Caroline Alves, Lennart Wissel, Philipp Capetian, Christiane Thielemann, 2022. Functional connectivity and convolutional neural networks for automatic classification of EEG data. Clinical Neurophysiology. 2022 (137), open access. 
    • Thomas Bouillet, Manuel Ciba, Caroline Alves, Francisco A. Rodrigues, Christiane Thielemann, Morvane Colin, Luc Buée, Sophie Halliez, 2022. Revisiting the involvement of tau in complex neural network remodeling: analysis of the extracellular neuronal activity in organotypic brain slice co-cultures. Journal of Neural Engineering. 2022 19(6), open access.
    • Caroline Alves, Aruane M. Pineda, Kirstin Roster, Christiane Thielemann, Francisco A. Rodrigues, EEG functional connectivity and deep learning for automatic diagnosis of brain disorders: Alzheimer’s disease and schizophrenia, Journal of Physics: complexity. 2022 (3), open access.
  • 2021

    • P. Ripka, V. Grim, M. Mirzaei, D. Hrakova, J. Uhrig, F. Emmerich, C. Thielemann, J. Hejtmánek, O. Kaman, R. Tesař: Modelling and measurement of magnetically soft nanowire arrays for sensor applications Nanosensors, 2021, open access.
    • Manuel Ciba, 2021. Synchrony Measurement and Connectivity Estimation of Parallel Spike Trains from in vitro Neuronal Networks. Julius-Maximilians-Universität Würzburg, open access.
  • 2020

    • D. Flachs, M. Lange, C. Thielemann: Biocompatible energy-harvester based on FEP-piezoelectrets ELAINE 2020 workshop Progress in electrically active implants - Tissue and functional regeneration, DFG/SFB 1270, Sept. 2020.
    • N. Krstic, J. Jüttner, A. Müller, M. Knuth, C. Thielemann: 3D printed hydrogel glucose sensor on argon plasma activated polystyrene, Lékař a technika - Clinician and Technology, accepted Sept. 2020
    • R. Bestel, U. van Rienen, C. Thielemann and R. Appali: Influence of neuronal morphology on the shape of extracellular recordings with Microelectrode Arrays: A finite element analysis, IEEE Transactions on Biomedical Engineering, DOI: 10.1016/j.neuro.2020.04.003. 
    • O. Smolin, M. Mayer, S. Ritter and C. Thielemann: Human induced pluripotent stem cell derived in vitro models for space radiation biology Investigation on Biological Effects of Radiation (IBER) Workshop 2020, GSI, Darmstadt
    • M. Mayer, O. Arrizabalaga, M. Ciba, I. S. Schroeder, S. Ritter and C. Thielemann: Novel in Vitro Assay to Investigate Radiation Induced Changes in the Functionality of Human Embryonic Stem Cell-Derived Neurospheres, Neurotoxicology. 2020; 79:40-47. DOI:10.1016/j.neuro.
    • F. Emmerich: Eigenschaften und Anwendungen von Dünnschicht Elektretmaterialien Dissertation, TU Darmstadt, 2020, DOI: 10.25534/tuprints-00012056
    • B. Körbitzer: Untersuchung funktioneller Schnittstellen zwischen Graphen und neuronalen Zellen, Dissertation TU Darmstadt, 2020, DOI: 10.25534/tuprints-00011462
    • M.Ciba, R. Bestel, C. Nick, G. F. Arruda, T. Peron, C. C. Henrique, L. F. Costa, F. A. Rodrigues, C. Thielemann: Comparison of different spike train synchrony measures regarding their robustness to erroneous data from bicuculline-induced epileptiform activity, Neural Computation, Volume 32, Issue 5, 2020. DOI: 10.1162/neco_a_01277 2019
    • O. Smolin, M. Mayer, F. Frieß, A. Heselich and C. Thielemann: Human induced pluripotent stem cell derived in vitro models for space radiation biology, Talk at International Biophysics Collaboration Meeting: book of abstracts.
  • 2019

    • S. Künzinger: Signal recording of 3D neurospheres on high-resolution CMOS MEA platform 23nd International Student Conference on Electrical Engineering POSTER 2019, Prag, Tschechien, 2019.
    • J. Jüttner and L. Kress: Functionalized Hydrogel as Glucose Imaging Sensor for in vitro Cell Cultures 23nd International Student Conference on Electrical Engineering POSTER 2019, Prag, Tschechien, 2019.
    • M. Ciba, M. Mayer, C. Thielemann: Experimental setup to investigate the effect of psychedelics on in vitro neuronal networks INSIGHT 2019, Berlin, 2019 D.
    • Flachs, F. Emmerich, G.-L. Roth, R. Hellmann and C. Thielemann: Laser-bonding of FEP/FEP interfaces for a flexible manufacturing process of ferroelectrets Journal of Physics: Conference Series 1407, 012107, 2019.
    • B. Körbitzer, P. Krauß, S. Belle, J. J. Schneider, C. Thielemann: Electrochemical Charaterization of Graphene Microelectrodes for Biological Applications, ChemNanoMat, 2019.
  • 2018

    • S. De Blasi, M. Ciba, A. Bahmer, C. Thielemann: Total Spiking Probability Edges: A Cross-Correlation based Method for Effective Connectivity Estimation of Cortical Spiking Neurons Journal of Neuroscience Methods, 312, 2019, 169-181. 2018
    • S. Allig, M. Mayer and C. Thielemann: Workflow for Bioprinting of Cell-laden Bioink Lekar a technika – Clinician and Technology, 2018, 48(2): 46–51.
    • D. Flachs, T. Köhler and C. Thielemann: Transparent poly(3,4-ethylenedioxythiophene)-based microelectrodes for extracellular recording Biointerphases, Volume 13, 2018.M. Ciba and C. Thielemann: Synchrony changes on different time-scales during in vitro neuronal network development Front. Cell. Neurosci. Conference Abstract: MEA Meeting, 2018.
    • M. Mayer, O. Arrizabalaga, I. Schröder, S. Ritter and C. Thielemann: Human Embryonic Stem Cell Derived Neurospheres – 2D and 3D Cell Culture in one sample Front. Cell. Neurosci. Conference Abstract: MEA Meeting, 2018.
    • J. Uhrig and F. Emmerich: Study on different template-based production processes for magnetic nanowires 22nd International Student Conference on Electrical Engineering POSTER 2018, Prag, Tschechien, 2018.
    • S. Allig, M. Mayer, C. Thielemann: Workflow for bioprinting of cell-laden bioink Lékař a technika – Clinician and Technology, vol. 48(2), pp. 46–51, 2018.
    • S. Allig: Controlled Cell Formation Using Bioprinting 22nd International Student Conference on Electrical Engineering POSTER 2018, Prag, Tschechien, 2018.
    • S. De Blasi: Simulation of Large Scale Neural Networks for Evaluation Applications 22nd International Student Conference on Electrical Engineering POSTER 2018, Prag, Tschechien, 2018.
    • A. Heselich, J. L. Frieß, S. Ritter, N. P. Benz, P. G. Layer and and C. Thielemann: High LET radiation shows no major cellular and functional effects on parimary cardiomyocytes in vitro Life Science in Space Research, Volume 16, Pages 93-100, 2018.
    • T. Köhler, M. Wölfel, M.Ciba, U. Bochtler and C. Thielemann: Terrestrial Trunked Radio (TETRA) exposure of neuronal in vitro networks. Environmental Research, Volume 162, Pages 1-7, 2018.
  • 2017

    M. Mayer, O. Arrizabalaga, F. Lieb, M. Ciba, S. Ritter and C. Thielemann: Electrophysiological investigation of human embryonic stem cell derived neurospheres using a novel spike detection algorithm Biosensors and Bioelectronics, Volume 100, p. 462-468, 2018. 2017

    F. Emmerich and C. Thielemann: Optimizing dimensions of unipolar Teflon-FEP piezoelectrets with micro-system-technology The 17th International Conference on Micro and Nanotechnology for Power Generation and Energy Conversion Applications - PowerMEMS 2017, Kanazawa, Japan, 2017.

    M. Ciba, T. Isomura, Y. Jimbo, A. Bahmer and C. Thielemann: Spike-contrast: A novel time scale independent and multivariate measure of spike train synchrony Journal of Neuroscience Methods, Volume 293, Pages 136–143, 2017.

    A. Bahmer and C. Thielemann: Application of spike train synchrony measure Spike-contrast to quantify the effect of bicuculline on cortical networks grown on microelectrode arrays CNS Conference, Antwerp, Belgium: BMC Neuroscience, P269, 2017.

    R. Bestel, R. Appali, U. van Riemen and C. Thielemann: Effect of morphologic features of neurons on extracellular electric potential: a simulation study using cable theory and electro-quasistatic equations Neural Computation, Volume 29, Issue 11, Pages 2955-2978, 2017.

    F. Emmerich and S. Ciba: Thin-film Micro-Heater for Fusion Bonding of Teflon-FEP foils 21th International Student Conference on Electrical Engineering POSTER 2017, Prag, Tschechien, 2017.

  • 2016

    • F. Lieb, H.-G. Stark and C. Thielemann: A stationary wavelet transform and a time-frequency based spike detection algorithm for extracellular recorded data Journal of Neural Engineering, Volume 14, Number 3,2016.
    • C. Thielemann and M. Kupnik: In vitro platform for acoustic and electrophysiological investigations of ultrasound stimulation 2nd International Brain Stimulation Conference, Barcelona, Spain, March2017 2016.
    • M. Mayer, O. Arrizabalaga, S. Ritter and C. Thielemann: Electrophysiological effects of ionizing radiation on neuronal network communication of human embryonic stem cell derived neurospheres GBS, Erlangen, Germany, 2016
    • B. Körbitzer, P. Krauß, J. J. Schneider and C. Thielemann: Characterization of graphene-coated microelectrode arrays for recording and stimulation of neuronal cells Front. Neurosci. Conference Abstract: MEA Meeting 2016
    • T. Köhler, M. Wölfel, U. Bochtler and C. Thielemann: TETRA specific long-term exposure of neuronal in vitro networks Conference paper, BioEM2016, Ghent, Belgium, 2016.
    • M. Mayer, O. Arrizabalaga, S. Ritter and C. Thielemann: Human Embryonic Stem Cell Derived Neurospheres – A Novel Three Dimensional Model For Neurotoxicological Studies Front. Neurosci. Conference Abstract: MEA Meeting 2016.
    • B. Koerbitzer, P. Krauss, C. Nick, S. Yadav, J. J. Schneider and C. Thielemann: Graphene electrodes for stimulation of neuronal cells 2D Materials, 2016, Volume 3, Number 2, Focus on Graphene-Based Biosensors, 2016.
    • S. Oster, A. W. Daus, C. Erbes, M. Goldhammer, U. Bochtler, and C. Thielemann: Long-term electromagnetic exposure of developing neuronal networks: A flexible experimental setup Bioelectromagnetics, Volume 37, Issue 4 Pages 201–280, 2016
    • C. Nick, H. Schlaak, and C. Thielemann: PEDOT:PSS coated Gold Nanopillar Microelectrodes with Ultralow Impedance for Neural Interfaces International Journal of Nanomanufacturing, 2016.
    • J. Frieß: Einfluss ionisierender Strahlung auf die elektrophysiologischen Eigenschaften kardialer Zellen. Dissertation TU Darmstadt, 2016.
    • F. Emmerich and C. Thielemann: Real-space measurement of potential distribution in PECVD-ONO electrets by Kelvin-Probe-Force-Microscopy Nanotechnology, 2016, Volume 27, Number 20.
    • C. Nick, B. Körbitzer, S. Yadav, P. Krauß, J. J. Schneider, and C. Thielemann: Carbon based nanostructures for biosensor applications NanoCarbon, Annual Conference, Würzburg, 2016.
    • D. Flachs and M. Ciba: Cell-based sensor chip for neurotoxicity measurements in drinking water Clinician and Technology, 2016, Vol. 46, No. 2.
    • M. Mayer, O. Arrizabalaga, S. Ritter and C. Thielemann: Human Embryonic Stem Cell Derived Neurospheres – A Novel Three Dimensional Model For Neurotoxicological Studies Front. Neurosci. Conference Abstract: MEA Meeting 2016 O. Arrizabalaga.
    • M. Mayer, S. Sadeghi, S. Kadereit, S. Ritter and C. Thielemann: Human embryonic stem cell-derived neural stem cells: a powerful model to investigate the regenerative capacity of the brain after an insult Symposium of International Society for Stem Cell Research (ISSRC), Dresden, 2016.
    • R. Samhaber, M. Schottdorf, A. El Hadya, K. Bröking, A. Daus, C. Thielemann, W. Stühmer, F. Wolf: Growing neuronal islands on multi-electrode arrays using an accurate positioning-µCP device Journal of Neuroscience Methods, Volume 257, 15 January 2016, Pages 194–203.
  • 2015

    • F. Emmerich and C. Thielemann: Patterning of PMMA by Gold-Nanoparticle initiated localized Decomposition 5th International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-Nano, Changchun, China, 2015.
    • C. Nick, C. Hock, F. Emmerich, S. Belle, T. Asmus, T. Loose, K.-H. Wienand and C. Thielemann: Ultrathin Gold as Sensor Platform for Biomolecules 5th International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-Nano, Changchun, China, 2015.
    • M. Mayer, O. Arrizabalaga, S. Sadeghi, S. Kadereit, S. Ritter and C. Thielemann: Human embryonic stem cell derived neurospheres form functional networks on microelectrode arrays GSI Scientific report, 2015
    • M. Mayer, O. Arrizabalaga, S. Sadeghi, S. Kadereit, S. Ritter and C. Thielemann: Human embryonic stem cell derived neurospheres: a powerful model to investigate ionizing radiation effects on neuronal differentiation GBS, Dresden, Germany, 2015
    • M. Mayer and C. Thielemann: In Vitro Untersuchungen zur Wirkung von dicht und dünn ionisierender Strahlung auf die frühe pränatale Entwicklung 2. Projektstatusgespräch zur BMBF-geförderten Nuklearen Sicherheitsforschung, Dresden, Deutschland, 2015
    • C. Nick: Mikrointegrierte Nanostrukturen mit hohem Aspektverhältnis als neuronale Schnittstelle Dissertation TU Darmstadt, 2015.
    • C. Nick, S. Yadav, R. Joshi, J.J. Schneider and C. Thielemann: A three-dimensional microelectrode array composed of vertically aligned ultra-dense carbon nanotube networks Applied Physics Letters, Volume 107, Issue 1, pp. 013101, 2015.
    • C. Nick, H.F. Schlaak and C. Thielemann: Simulation and Measurement of Neuroelectrodes Characteristics with Integrated High Aspect Ratio Nano Structures AIMS Material Science, Volume 2, Issue 3, pp. 189-202, 2015.
    • B. Körbitzer, P. Krauß, C. Nick, J. J. Schneider and C. Thielemann: Graphene electrodes for recording and stimulation of neural cells ICREA Workshop on Graphene Nanobiosensors, Barcelona, Spanien, 2015.
  • 1994 - 2014

    2014:

    • J. L. Frieß, A. Heselich, S. Ritter, A. Haber, N. Kaiser, P. G. Layer and C. Thielemann: Electrophysiologic and cellular characteristics of cardiomyocytes after X-ray irradiation Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Volume 777, pp. 1–10, 2015. 2014.
    • M. Mayer, S. Ritter and C. Thielemann: Electrophysiological Effects of Ionizing Radiation on the Network Development of Neurons in vitro GBS, Tübingen, Germany, 2014.
    • J. L. Frieß, A. Heselich, S. Ritter, P. G. Layer and C. Thielemann: Combined effects of ionizing radiation and cardio-active drugs on human iPSC-derived cardiomyocytes GSI Scientific Report, 2014.
    • A. Helm, S. Frank, J. Frieß, C. Thielemann, M. Durante and S. Ritter: Electrophysiological response of mouse embryonic stem cell-derived cardiomyocytes after X-ray and C-ion exposure GSI Scientific Report, 2014.
    • M. Mayer, B. Müller, S. Kadereit, S. Ritter and C. Thielemann: Human neurospheres on microelectrode arrays: a model to investigate ionizing radiation effects on neuronal network communication GSI Scientific Report, 2014.
    • C. Nick, S. Yadav, R. Joshi, C. Thielemann and J.J. Schneider: Growth of Cortical Neurons Grown on Randomly Oriented and Vertically Aligned Dense Carbon Nanotube Networks Beilstein Journal of Nanotechnology, Volume 5, 2014.
    • C. Nick and C. Thielemann: Are Carbon Nanotube Microelectrodes Manufactured from Dispersion Stable Enough for Neural Interfaces? BioNanoScience, Volume 4, Issue 3, 2014.
    • F. Emmerich and C. Thielemann: Direct Visualisation of Stored Charges in PECVD ONO-Layers by Kelvin-Probe-Force-Microscopy 15th International Symposium on Electrets ISE, Baltimore, USA, 2014.
    • C. Nick, H.F. Schlaak and C. Thielemann: PEDOT:PSS coated Gold Nanopillar Micro-electrodes for Neural Interfaces (invited talk) 4th International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-Nano, Taipeh, Taiwan, 2014.
    • M. Stern, C. Nick, R.Bestel and C. Thielemann: A Novel LabVIEW based Multi-Channel Closed-Loop Stimulator 9th International Meeting on Substrate-Integrated Micro-electrode Arrays, Reutlingen, 2014.
    • C. Nick, P. Lippert, S. Quednau, H.F. Schlaak and C. Thielemann: Gold Nanopillar Microelectrodes on Low Temperature Curing Polyimide for the Interface with Electrogenic Cells Middle East Conference on BioMedical Engineering MECBME, 2014.
    • A. Daus, R. Bestel and C. Thielemann: A multivariate spike-detection algorithm to assess activity patterns of three-dimensional in vitro models MEA Meeting, Reutlingen, 2014. 

    2013:

    • M. Mayer, S. Ritter, S. Kadereit, C. Thielemann: Electrophysiological Effects of Ionizing Radiation on the Early Prenatal Development in human embryonic stem cells in vitro GBS, Darmstadt, Germany, 2013
    • A.W. Daus: Zellbasierte Biosensoren - Hybride Systeme aus dreidimensionalen in vitro Netzwerken und Mikroelektroden Arrays Dissertation TU Darmstadt, 2013.
    • C. Nick, M. Goldhammer, R. Bestel, F. Steger, A.W. Daus and C. Thielemann: DrCell – A Software Tool for the Analysis of Cell Signals recorded with Extracellular Microelectrodes Signal Processing: An International Journal (SPIJ) 7(2), 96-109, 2013.
    • C. Nick, S. Quednau, R. Sarwar, H. F. Schlaak and C. Thielemann: High Aspect Ratio Gold Nanopillars on Microelectrodes for Neural Interfaces Microsystems Technologies, 20 (10-11), 1849-1857, 2014 (online 11/2013), DOI: 10.1007/s00542-013-1958-x.
    • A. Helm, S. Frank, J Frieß, C. Thielemann, M. Durante and S. Ritter: Purified cultures of mouse embryonic stem cell-derived cardiomyocytes of electrophysiological studies with ionizing radiation GSI Scientific Report, 2013.
    • J Frieß, A Heselich, S. Ritter, P. G. Layer and C. Thielemann: Effect of X-rays and titanium ions on cardiomyocyte cultures GSI Scientific Report, 2013.
    • M. Mayer, S. Ritter and C. Thielemann: Electrophysiological Effects of Ionising Radiation on Cortical Rat Neurons in vitro GSI Scientific Report, 2013.
    • J. Frieß, A. Heselich, S. Ritter and C. Thielemann: Electrophysiological characteristics of cardiomyocytes after heavy ion exposure GBS, Darmstadt, Germany, 2013.
    • S. Oster, A. W. Daus, M. Goldhammer, U. Bochtler and C. Thielemann: A Flexible RF Exposure Setup for Long-term Electrophysiological Investigations on Biological Samples in vitro Progress in Electromagnetics Research Symposium, Stockholm, Sweden, 2013.
    • C. Nick, S. Quednau, R. Sarwar, C. Thielemann and H. F. Schlaak: Gold-Nanodrähte auf Mikroelektroden zur extrazellulären Ableitung elektrogener Zellen Mikrosystemtechnik Kongress, VDE Verlag GmbH, 2013.
    • J. Frieß, A. Heselich, S. Ritter, A. W. Daus, P. G. Layer and C. Thielemann: Electrophysioliogic and Molecular Characteristics of Cardiomyocytes after Heavy Ion Irradiation in the frame of the ESA IBER-10 Program Heavy Ion in Therapie and Space Radiation Symposium, Chiba, Japan, 2013.
    • J. Obmann, C. Polt, T. Loose, T. Asmus, K. Wienand and C. Thielemann: Novel Resistive Bioaffinity Sensor based on Ultra-Thin Gold Films 3rd International Conference on Bio-Sensing Technology, Sitges, Spain, 2013.
    • C. Nick, S. Quednau, R. Sarwar, C. Thielemann and H. F. Schlaak: Fabrication of High Aspect Ratio Gold Nanopillars on Micro-electrodes for the Interface with Electrogenic Cells HARMNST-10th International Workshop on High Aspect Ratio Micro and Nano System Technologies, Berlin, Germany, p. 212–213, 2013.
    • C. Nick, R. Bestel, F. Steger and C. Thielemann: Spike Detection, Sorting and Propagation of Cell Signals Recorded with Extracellular Microelectrodes Engineering in Medicine and Biology Society. IEMBS’13. 35th Annual International Conference of the IEEE, 2013.

    2012:

    • M. Materna, A. Helm, P. Hessel, J. Frieß, C. Thielemann, D. Pignalosa, W. Mäntele, M. Durante and S. Ritter: First electrophysiological studies on mouse embryonic stem cell-derived cardiomyocytes GSI Scientific Report 2012.
    • J. Frieß, A. Heselich, S. Ritter, A. W. Daus, P.G. Layer and C. Thielemann: Electrophysiological Effects of Heavy Ion Irradiation on Cardiomyocytes GSI Scientific Report 2012.
    • O. Yilmazoglu, R. Joshi, C. Nick, S. Al-Daffaie, S. Yadav, C. Thielemann, J.J. Schneider and H.L. Hartnagel: CNT photocathodes based on GaAs high-frequency photoswitches 25th International Conference of the IEEE on Vacuum Nanoelectronics Conference, Jeju, South Korea.
    • C. Nick, R. Joshi, J.J. Schneider and C. Thielemann: Three-Dimensional Carbon Nanotube Electrodes for extracellular Recording of Cardiac Myocytes Biointerphases, 2012, DOI 10.1007/s13758-012-0058-2.
    • R. Bestel, A. W. Daus and C. Thielemann: A novel automated spike sorting algorithm with adaptable feature extraction Journal of Neuroscience Methods, 211 (1), 168–178, 2012. A. Daus: Leben auf dem Mikrochip – Biosensoren auf der Basis von Mikroelektroden-Arrays Labor & More 8/2012.
    • C. Nick, R. Joshi, J. Schneider and C. Thielemann: Low Temperature Substrate Transfer Technique for 3D Vertically Aligned Carbon Nanotube Architectures Int. J. Surface Science and Engineering, Vol. 6, No. 3, 2012, p.246, 2012.
    • A. W. Daus, P. G. Layer and C. Thielemann: A spheroid-based biosensor for the label-free detection of drug-induced field potential alterations Sensors and Actuators B, 165: 53– 58, 2012.
    • S. Ritter, M. Durante, A. Helm, F. Steger, A. W. Daus, J. Friess and C. Thielemann: Assessment of cardiotoxicity of heavy ions in vitro: generation andelectrophysiology of cardiomyocytes 39th COSPAR Scientific Assembly, Mysore, India, 2012.
    • F. Steger, J. Frieß, A.W. Daus, S. Ritter, and C. Thielemann: Analysis of electrophysiological characteristics of cardiomyocytes following radiation exposure MEA Meeting, Reutlingen, Germany, 2012.
    • C. Thielemann, S. Ritter, P. Layer, J. Frieß, A. W. Daus, F. Steger and A. Heselich: IBER10 - Cellular effects of space radiation with relevance to cardiovascular diseases ESA Conference, Life in Space for Life on Earth, Aberdeen, Scottland, 2012.
    • C. Nick, T. Heinlein, J. J. Schneider and C. Thielemann: 3D Carbon Nanotube Electrodes for Sensing of Neural Activity Biosensors, Cancun, Mexico, 2012.

    2011:

    • C. Thielemann, S. Ritter and P. Layer, J. Frieß, A. Daus, F. Steger and A. Heselich: Cellular effects of space radiation with relevance to cardiovascular diseases GSI Scientific Report, 2011.
    • F. Steger, S. Ritter, A. Daus, J. Frieß and C. Thielemann: Analysis of electrophysiological characteristics of cardiomyocytes following radiation exposure GSI Scientific Report, 2011.
    • A. W. Daus, M. Goldhammer, P.G. Layer and C. Thielemann: Electromagnetic exposure of scaffold-free three-dimensional cell culture systems  Bioelectromagnetics, 32: 351–359, 2011.
    • C. Nick, R. Joshi, J.J. Schneider and C. Thielemann: Multielektroden Array mit Elektroden aus vertikalen Kohlenstoff Nanoröhren für die extrazelluläre Ableitung von Aktionspotentialen Mikrosystemtechnik Kongress, VDE Verlag GmbH, 2011.
    • C. Nick, R. Joshi, J.J. Schneider, H.F. Schlaak and C. Thielemann: Niedrigtemperatur-Transfer von individuell adressierbaren Strukturen von vertikal ausgerichteten Kohlenstoff-Nanoröhren GMM-Workshop Mikro-Nano-Integration, VDE Verlag GmbH, 2011.
    • A. Daus, R. Bestel and C. Thielemann: Spike Detection, Refinement And Interpretation Of Recordings In Three-Dimensional In Vitro Systems RMSC, Beijing, China, 2011.
    • F. Emmerich and C. Thielemann: Observation of Thermal Discharge in Nanopatterned Electrets by Kelvin-Probe-Microscopy 14th International Symposium on Elecrets ISE, Montpellier, France, 2011.

    2010:

    • A. W. Daus, M. Goldhammer, U. Bochtler and C. Thielemann: A new approach for the investigation of long-term effects of RF radiation on cells 28th PIER, Cambridge, USA, 2010.

    2009:

    • M. Jungblut, W. Knoll, C. Thielemann and M. Pottek: Triangular neuronal networks on microelectrode arrays: an approach to improve the properties of low-density networks for extracellular recording Biomedical Devices, Volume 11, Number 6, 1269 -1278, 2009.
    • A. W. Daus, M. Hasenkopf and C. Thielemann: Novel 3D Cell Culture Systems for Electromagnetic Exposure Studies BioEM, Davos, Switzerland, 2009.
    • M. Goldhammer, A.W. Daus, C. Thielemann and U. Bochtler: Flexible Measurement Setup for Electromagnetic Exposition of Biological Samples BioEM, Davos, Switzerland, 2009.
    • A. W. Daus, M. Goldhammer, U. Bochtler and C. Thielemann: Electromagnetic Exposition of Neuronal Networks in vitro Forschungsgemeinschaft Funk, Radiofrequency Fields and Health, Stuttgart, Germany, 2009.
    • F. Arnheiter, T. Asmus, T. Loose, K. Wien and, C. Thielemann: Metal-Nanosensor for the Detection of Biomolecules Mikro-Nano Integration (GMM-FB60), ISBN 978-3-8007-3155-8, Seeheim, Germany, 2009.

    2006:

    • M. Pottek, P. Soerensen, W. Knoll, S. Howitz, C. Thielemann: Cell-based Microfluidic System for Drug Screening Applications MST news, January 2006, 38-39.
    • C. Thielemann, Kapitel "BioMEMS" in Praxiswissen Mikrosystemtechnik, Friedemann Völklein, Vieweg Verlag, Feb 2006, ISBN 3528138912.

    2005:

    • M. Pax, J. Rieger, C. Thielemann and D. Johannsmann: Cell-Based Biosensor for Drug Screening: Detection of the Beating Rate of Cardiac Myocytes with a Quartz Crystal Resonator Analyst, 2005, 130, 1451 - 1458.
    • J. Li, C. Thielemann, U. Reuning, and D. Johannsmann: Monitoring of Integrin-Mediated Adhesion of Human Ovarian Cancer Cells to Model Protein Surfaces by Quartz Crystal Resonators: Evaluation in the Impedance Analysis Mode Bioelectronics and Biosensors, Volume 20, Issue 7, 2005, 1333-1340. 
    • https://doi.org/10.1016/j.bios.2004.05.004

    1997:

    • C. Thielemann and G. Hess: Inorganic electret membrane for a silicon microphone Sensors and Actuators A: Physical, Volume 61, Issues 1–3, June, p. 352-355, 1997.

    1996:

    • H. Amjadi and C. Thielemann: Silicon-based inorganic electrets for application in micromachined devices IEEE Transactions on Dielectrics and Electrical Insulation, vol. 4, No. 4, p. 494, 1996.

    1994:

    • R. Schellin, G. Hess, W. Kühnel, C. Thielemann, D. Trost, J. Wacker and R. Steinmann: Measurements of the mechanical behaviour of micromachined silicon and silicon-nitride membranes for microphones, pressure sensors and gas flow meters Sensors and Actuators A: Physical, Volume 41, Issues 1–3, p. 287–292, 1994.